Skip to main content
. Author manuscript; available in PMC: 2012 May 7.
Published in final edited form as: J Theor Biol. 2011 Feb 3;276(1):199–208. doi: 10.1016/j.jtbi.2011.01.054

Figure 4.

Figure 4

The x-axis represents the number of hours after initial exposure at which treatment is started. This ranges from 12 hours after exposure up to 72 hours after exposure. The y-axis indicates the minimum duration (in days) of treatment needed for survival given one of four different initial spore counts, S(0), ranging from 4500 to 2×107. For example, consider the third set of columns above 36. Treatment began 36 hours after exposure. At least 1 day of Doxycycline treatment is needed if S(0)=4500, 42 days if S(0)=9000, and greater than 73 days if S(0)=2×104 or S(0)=2×107. In the latter two cases, we assume that such lengthy treatment for this antibiotic is unreasonable and that the subject would have already died before completion of the antibiotic regimen.