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. Author manuscript; available in PMC: 2013 Feb 5.
Published in final edited form as: Virology. 2011 Dec 20;423(1):77–88. doi: 10.1016/j.virol.2011.11.019

Fig 7.

Fig 7

Histopathological and immunohistochemical analyses of the lungs obtained from the mice inoculated with the H4N8 isolate and the reference viruses. Hematoxylin and eosin staining of the lung of the control mouse (A) and the mouse infected with 6KS0185 (B). Detection of the viral antigen in the lungs of the mice inoculated with 6KS0185 (C), A/duck/Osaka/1/05 (D), A/duck/Shiga/8/04 (E), and A/duck/Czechoslovakia/56 (F). The tissue samples were collected from the mice 4 or 5 days after the intranasal inoculation of the viruses (103 TCID50). The results are of a representative mouse of each group (n = 4). Arrows indicate the viral antigen detected by polyclonal antibody against influenza A virus. The scale bar represents 200 μm.