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. Author manuscript; available in PMC: 2013 Jan 4.
Published in final edited form as: Cell Metab. 2011 Dec 22;15(1):65–74. doi: 10.1016/j.cmet.2011.11.010

Figure 3. Gene expression changes due to hepatic FoxO1 ablation.

Figure 3

(A) Gene ontology enrichment analysis, based on microarrays of liver tissue from WTD-fed L-FoxO1 and L-FoxO1:Ldlr−/− versus littermate controls. Only non-redundant pathways, where P< 0.001 for the pathway, are shown. (B–D) Relative hepatic gene expression by qPCR in (B) WTD-fed L-FoxO:Ldlr−/−, (C) WTD-fed L-FoxO1, and (D) chow-fed L-FoxO1 mice. (E) Relative gene expression by qPCR in ileum from WTD-fed L-FoxO1 mice. (n=6–7 for all) *P <0.05, **P < 0.01, ***P < 0.001, by Student's t-tests. Data are presented as mean ± S.E.M.