TABLE 1.
MEAN (+STANDARD DEVIATION) DEMOGRAPHIC AND CLINICAL FEATURES IN CONTROLS AND LEWY BODY SPECTRUM DISORDER PATIENTS
| PARKINSON’S DEMENTIA/ LEWY BODY DISEASE |
PARKINSON’S DEMENTIA |
LEWY BODY DISEASE |
PARKINSON’S DISEASE |
CONTROL | |
|---|---|---|---|---|---|
| AGE | 73.8 (6.5)1 | 74.8 (7.3) | 72.9 (5.9) | 65.6 (8.2) | 63.9 (9.5) |
| EDUCATION | 16.1 (2.9) | 16.3 (3.3) | 16.0 (2.6) | 15.8 (3.2) | 15.2 (2.3) |
| MMSE | 25.1 (3.2)1,2 | 26.5 (2.4) | 23.8 (3.4) | 28.3 (1.8)1 | 29.4 (0.7) |
| MOTOR | |||||
| UPDRS | 25.21 (11.67) | 31.9 (13.5) | 18.6 (3.0) | 25.00 (8.38) | - |
| Hoehn & Yahr score | 2.5 (0.67) | 2.3 (0.8) | 2.7 (0.4) | 2.12 (0.65) | - |
| NEUROPSYCHOLOGY | |||||
| Trails B | −7.32 (17.1) | −2.9 (5.6) | −11.2 (22.8) | −1.23 (3.7) | - |
| Stroop | −4.7 (9.4) | 0.2 (0.7) | −9.0 (11.5) | 0.11 (0.93) | - |
| Sentence grammatical comprehension | −4.04 (3.42) | −2.5 (3.5) | −5.6 (3.1) | −0.29 (1.76) | - |
| Sentence-picture match | −3.47 (5.26) | −1.8 (2.1) | −5.6 (7.6) | −0.24 (2.12) | - |
| Pyramid and palm tree | −5.26 (5.69) | −2.4 (2.1) | −8.1 (6.8) | −1.31 (1.4) | - |
| Semantic categorization | −2.21 (3.33) | −2.9 (3.9) | −1.2 (2.3) | −0.07 (1.01) | - |
1
NOTE Differs from controls at p<0.01, according to a t-test
2
Differs from non-demented PD patients at p<0.01, according to a t-test
3
Neuropsychology values are z-scores relative to age- and education-matched controls, where z<−1.96 differs from controls at a p-value of 0.05.