TABLE 3.
PEAK COORDINATES OF SIGNIFICANT AREAS OF CORTICAL THINNING IN LEWY BODY SPECTRUM DISORDER, AND SIGNIFICANT REGRESSIONS RELATING CORTICAL THINNING TO SENTENCE PROCESSING PERFORMANCE
| Anatomic Locus (Brodmann Area) | Coordinates | z-score | Cluster Size (voxels) | ||
|---|---|---|---|---|---|
| x | y | z | |||
| LEWY BODY SPECTRUM DISORDER ATROPHY | |||||
| L inferior frontal (47) | −63 | 2 | −4 | 4.19 | 3477 |
| L inferior frontal (47/11/38) | −52 | 22 | −12 | 4.07 | 4331 |
| L inferior frontal (47/45) | −56 | 33 | −2 | 3.87 | 1234 |
| L inferior frontal (47) | −49 | 14 | −1 | 3.47 | 197 |
| L inferior frontal (11) | −35 | 40 | −18 | 3.09 | 310 |
| L inferior frontal (10/11) | −32 | 55 | −10 | 3.65 | 599 |
| L dorsolateral prefrontal (45/10) | −46 | 40 | 19 | 3.78 | 451 |
| L dorsolateral prefrontal (9/46) | −51 | 16 | 27 | 3.49 | 890 |
| L dorsolateral prefrontal (8) | −32 | 21 | 46 | 3.56 | 247 |
| L medial frontal (10) | −6 | 46 | 10 | 3.42 | 290 |
| L medial frontal (11/10) | −4 | 48 | −14 | 3.78 | 1104 |
| L anterior cingulate (24/32) | −7 | 3 | 37 | 3.24 | 504 |
| L insula (13) | −45 | −15 | 15 | 3.13 | 638 |
| R inferior frontal (45/44/47) | 56 | 19 | 5 | 4.73 | 11918 |
| R dorsolateral prefrontal (9/46) | 45 | 31 | 26 | 3.69 | 1171 |
| R dorsolateral prefrontal (10) | 34 | 56 | 11 | 3.11 | 444 |
| R dorsal frontal (6) | 33 | −2 | 45 | 3.19 | 241 |
| R medial frontal (10/32) | 10 | 50 | −1 | 3.18 | 681 |
| R medial frontal (9/10) | 1 | 58 | 30 | 3.12 | 1147 |
| L posterolateral temporal (37/27) | −23 | −36 | −8 | 4.05 | 3790 |
| L posterolateral temporal (20/21) | −42 | −1 | −39 | 3.76 | 1539 |
| L posterolateral temporal (22/40) | −60 | −51 | 22 | 3.46 | 719 |
| L posterolateral temporal (21) | −63 | −45 | −3 | 3.42 | 743 |
| L posterolateral temporal (21/20) | −67 | −37 | −18 | 3.31 | 202 |
| L posterolateral temporal (21/20) | −57 | −10 | −19 | 3.13 | 277 |
| L anterior temporal (38/13) | −30 | 5 | −12 | 3.34 | 1562 |
| L medial temporal (36/28) | −24 | −8 | −31 | 3.61 | 659 |
| L temporal-occipital (37/19) | −44 | −58 | −10 | 3.29 | 978 |
| R posterolateral temporal (21/22) | −50 | −77 | −3 | 3.96 | 1233 |
| R posterolateral temporal (37/20) | 46 | −55 | −16 | 3.51 | 2142 |
| R posterolateral temporal (21/22) | 67 | −35 | 1 | 3.45 | 1309 |
| R posterolateral temporal (21/20) | 65 | −43 | −10 | 3.45 | 339 |
| R posterolateral temporal (40/42) | 63 | −27 | 23 | 3.26 | 852 |
| R anterior temporal (21/22) | 58 | −3 | −5 | 4.02 | 14484 |
| R middle temporal (20) | 40 | −12 | −31 | 3.18 | 946 |
| R temporal-occipital (21/37) | −20 | −99 | 11 | 3.43 | 3040 |
| L inferior parietal (43/40) | −67 | −15 | 18 | 3.58 | 693 |
| L inferior parietal (40/2/1) | −59 | −22 | 24 | 3.49 | 967 |
| L superior parietal (2/40) | −63 | −25 | 36 | 3.34 | 730 |
| L anterior parietal (2/1/3) | −54 | −19 | 48 | 3.71 | 2018 |
| L lateral parietal-occipital (19) | 40 | −20 | 48 | 3.91 | 378 |
| R parietal-occipital (19/18/37) | 30 | −71 | 39 | 3.88 | 6768 |
| L lateral occipital (18) | −40 | −91 | −4 | 3.37 | 683 |
| L medial occipital (18) | −7 | −72 | −3 | 3.80 | 182 |
| L medial occipital (17) | −22 | −96 | −11 | 3.18 | 124 |
| R medial occipital (18) | 6 | −76 | −1 | 3.89 | 392 |
| R medial occipital (18/17) | 12 | −97 | 9 | 3.36 | 1040 |
| R medial occipital (19) | 19 | −89 | 32 | 3.20 | 1357 |
| R medial occipital (19) | 7 | −83 | 36 | 3.18 | 651 |
| R medial occipital (18/17) | 8 | −94 | −7 | 3.13 | 1411 |
| R posterior cingulate (31) | 3 | −59 | 25 | 3.14 | 1426 |
| REGRESSION ANALYSES | |||||
| EXPERIMENTAL SENTENCES LENGTHENED AT THE CRITICAL LOCUS OF AMBIGUITY RESOLUTION | |||||
| L dorsolateral prefrontal (45) | −51 | 20 | 20 | 3.16 | 57 |
| L medial frontal (11) | −8 | 17 | −24 | 3.21 | 156 |
| R frontal (4) | 50 | −8 | 40 | 3.26 | 71 |
| R inferior parietal (40) | 53 | −29 | 22 | 3.16 | 63 |