Table 3.

Odds ratios (95% CI) for any depression (probable minor or major) or antidepressant use and major depression (probable major depression or antidepressant use) among pregnant women (N = 2398) with pre-existing (N = 418) or pregnancy-related hypertension (N = 347) versus those with no hypertension – using multiple imputation

	Any depression (minor of major) or antidepressant usea N = 327 (13.6%)		Major depression or antidepressant useb N = 235 (9.8%)
	Pre-existing HTN	Pregnancy- related HTN	Pre-existing HTN	Pregnancy-related HTN
Unadjusted	1.84h (1.39 – 2.44)	1.15 (0.82 – 1.62)	1.82h (1.31 – 2.51)	1.29 (0.88 – 1.90)
Adjusted for
Demographicsc	1.82h (1.36 – 2.44)	1.12 (0.79 – 1.59)	1.76h (1.26 – 2.45)	1.24 (0.84 – 1.84)
Demographics +chronic conditionsd	1.57h (1.15 – 2.13)	1.04 (0.73 – 1.49)	1.54f (1.08 – 2.18)	1.17 (0.78 – 1.74)
Demographics + chronic conditionsd + current smoking	1.55g (1.13 – 2.12)	1.04 (0.72 – 1.49)	1.52* (1.07 – 2.16)	1.17 (0.78 – 1.74)
Demographics + chronic conditionsd + current smoking + pregnancy characteristicse	1.55g (1.08 – 2.23)	0.92 (0.59 – 1.44)	1.65f (1.10 – 2.48)	1.06 (0.65 – 1.73)

^aMajor depression, minor depression, or antidepressant use vs. no depression

^bMajor depression or antidepressant use vs. no major depression

^cDemographic characteristics: maternal age at depression screen (years), marital status (married or partnered, single), non-white race/ethnicity, education (some college, high school or less), employment (yes, no)

^dNumber of chronic conditions out of 11

^ePregnancy characteristics: prior pregnancy (yes, no), gestational week at depression screen (weeks), ≥1 prior pregnancy complication (yes, no)

^fp <0.05

^gp <0.01

^hp <0.001