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. Author manuscript; available in PMC: 2013 Jan 1.
Published in final edited form as: Trends Cell Biol. 2011 Dec 15;22(1):42–49. doi: 10.1016/j.tcb.2011.11.001

Figure 3. Interplay between the germline and the soma in the regulation of longevity by ASH-2 complex deficiency.

Figure 3

In adult worms, longevity by deficiencies in the ASH-2 complex requires an intact germline with continuous egg production. It is possible that unknown ‘pro-longevity’ signals are emitted from the fertilized eggs when ASH-2 complex members are deficient, thereby delaying aging of the soma. KD: knock-down.