Table 2.
Multivariable logistic regression models of the odds of low cognitive score (0–5) in the non-CKD and CKD subpopulations
| Non-CKD subpopulation |
CKD subpopulation |
|||
|---|---|---|---|---|
| OR | 95% CI | OR | 95% CI | |
| Demographic | ||||
| Each additional year in age | 1.08 | 1.04–1.11 | 1.05 | 0.98–1.12 |
| Male vs. female | 1.94 | 1.28–2.96 | 1.19 | 0.45–3.14 |
| African-American race vs. Caucasian | 2.81 | 1.69–4.69 | 2.74 | 1.25–6.04 |
| Education (<12 years) | 3.13 | 1.89–5.21 | 7.23 | 2.52–20.7 |
| Family income (USD <20,000/year) | 1.90 | 1.09–3.31 | 1.41 | 0.66–3.02 |
| Clinical and laboratory variables | ||||
| Myocardial infarction | 2.11 | 1.08–4.14 | 0.37 | 0.15–0.93 |
| Stroke | 1.44 | 0.73–2.84 | 0.48 | 0.16–1.44 |
| Congestive heart failure | 0.94 | 0.37–2.41 | 1.07 | 0.44–2.60 |
| Diabetes | 1.41 | 0.77–2.58 | 0.68 | 0.29–1.59 |
| Hypertension | 0.73 | 0.41–1.29 | 1.44 | 0.51–4.06 |
| Physical inactivity | 1.78 | 1.12–2.84 | 2.46 | 1.31–4.63 |
| Current alcohol use | 0.97 | 0.60–1.59 | 0.75 | 0.28–1.99 |
| History of smoking | 1.32 | 0.68–2.56 | 0.53 | 0.18–1.57 |
| Each ml/min/1.73 m2 increase in eGFR | 1.01 | 0.99–1.02 | 1.00 | 0.97–1.03 |
| Each doubling of urinary ACR, mg/g | 1.10 | 0.94–1.28 | 1.02 | 0.84–1.24 |
| Each ng/ml increase in serum 25-OH vitamin D | 1.00 | 0.97–1.03 | 0.98 | 0.95–1.01 |
| Each g/dl increase in hemoglobin | 0.81 | 0.67–0.99 | 1.00 | 0.80–1.24 |
| Each doubling of CRP, mg/1 | 0.94 | 0.81–1.09 | 0.92 | 0.73–1.16 |
ACR = Albumin to creatinine ratio.