Figure 5.

Relative gene expression for the specified target genes in comparison to the endogenous control ACTB. A comparison of gene expression in macrophages from healthy and HIV-infected subjects demonstrates reduced gene expression for all genes involved in the de novo synthesis of GSH in macrophages from HIV-infected subjects. A greater than 3-fold increase in GSR expression is observed in HIV-infected macrophages. Results are from n = 3 individuals for both healthy and HIV-infected macrophages.