Table 3.
Variables | N | Cases/Controls | DD+DI vs II | DD vs DI+II | DD vs II | D vs I | DI vs II | |||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
OR(95%CI) | P* | OR(95%CI) | P* | OR(95%CI) | P* | OR(95%CI) | P* | OR(95%CI) | P* | |||
Total | 25 | 3914/11391 | 0.88(0.73, 1.06) | 0.38 | 0.93(0.80, 1.09) | 0.39 | 0.90(0.73, 1.12) | 0.34 | 0.94(0.83, 1.07) | 0.34 | 0.89(0.75, 1.06) | 0.20 |
Subgroup by ethnicity | ||||||||||||
Asian | 8 | 1201/1950 | 1.13(0.96, 1.33) | 0.15 | 1.05(0.74, 1.49) | 0.78 | 1.09(0.83, 1.44) | 0.53 | 1.08(0.93, 1.25) | 0.34 | 0.85(0.68, 1.06) | 0.14 |
European | 14 | 2188/8130 | 0.89(0.73, 1.09) | 0.26 | 0.89(0.73, 1.09) | 0.26 | 0.76(0.53, 1.08) | 0.12 | 0.86(0.71, 1.03) | 0.10 | 0.78(0.60, 1.01) | 0.06 |
Subgroup by cancer type | ||||||||||||
Lung | 7 | 737/6511 | 1.04(0.70, 1.55) | 0.85 | 0.99(0.67, 1.48) | 0.98 | 1.02(0.62, 1.69) | 0.93 | 1.03(0.80, 1.31) | 0.83 | 1.01(0.64, 1.61) | 0.95 |
Breast | 5 | 1235/8057 | 0.88(0.71, 1.09) | 0.24 | 0.95(0.75, 1.21) | 0.70 | 0.86(0.64, 1.16) | 0.33 | 0.94(0.81, 1.09) | 0.41 | 0.88(0.72, 1.09) | 0.24 |
Colorectal | 4 | 517/6456 | 0.81(0.53, 1.24) | 0.34 | 0.83(0.66, 1.05) | 0.11 | 0.73(0.45, 1.18) | 0.20 | 0.87(0.71, 1.06) | 0.17 | 0.87(0.58, 1.31) | 0.50 |
Gastric | 3 | 434/775 | 1.06(0.71, 1.59) | 0.78 | 0.94(0.66, 1.36) | 0.76 | 0.96(0.55, 1.65) | 0.87 | 1.00(0.74, 1.34) | 1.00 | 1.12(0.79, 1.58) | 0.52 |
Prostate | 3 | 276/6094 | 2.44(0.66, 8.97) | 0.18 | 2.05(0.74, 5.62) | 0.17 | 3.48(0.63, 19.13) | 0.15 | 2.05(0.84, 5.02) | 0.11 | 1.66(0.67, 4.07) | 0.27 |
*: P value for Q-test.