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Expected equilibrium frequency of the disease phenotype caused by an overdominant antagonistically pleiotropic allele. Equilibrium frequencies for heterozygous advantages, Sadv, of 0.1%, 1%, 5% and 25% are shown for a range of homozygous deleterious effects, Sdel, ranging from 0% (no deleterious effect) to 100% (allele is lethal or homozygotes are always sterile). Note the Log10 scale on the Y-axis.
