Table 3.
Multiple linear regression model to evaluate predictors for baseline total SGRQ and after three years follow-up (n = 95)
| Variables | Baseline total SGRQ Coefficient (95% CI) | p-value | Final total SGRQ Coefficient (95% CI) | p-value |
|---|---|---|---|---|
| Male | 1.11 (-6.32, 8.56) | 0.766 | -1.02 (-7.67, 5.62) | 0.760 |
| Age (y) | -0.51 (-1.05, 0.01) | 0.059 | -0.14 (-0.67, 0.37) | 0.570 |
| Smoking | 5.68 (-1.55, 12.93) | 0.122 | 1.96 (-5.46, 9.40) | 0.600 |
| SpO2 (%) | -0.22 (-1.29, 0.84) | 0.675 | -0.27 (-0.91, 0.36) | 0.395 |
| FEV1 (%) | -0.11 (-0.25, 0.25) | 0.105 | -0.18 (-0.32, -0.05) | 0.007 |
| 6MWD (m) | -0.01 (-0.05, 0.03) | 0.731 | 0.01 (-0.02, 0.56) | 0.426 |
| BMI (kg/m2) | -0.24 (-0.75, 0.23) | 0.349 | 0.18 (-0.34, 0.72) | 0.489 |
| MMRC (score) | 11.72 (8.17, 15.26) | < 0.001 | 10.44 (7.08, 13.80) | < 0.001 |
| Charlson index | -1.16 (-3.82, 1.48) | 0.384 | -0.39 (-3.10, 2.30) | 0.770 |
SpO2: pulse oximetry; FEV1: forced expiratory volume in the first second (% of predicted); 6MWD: six-minute walking distance; BMI: body mass index; MMRC: Modified Medical Research Council; Baseline (R2 = 0.58; p < 0.05); After three years (R2 = 0.61; p < 0.05).