Table 5.
Fatty Acid Composition of Serum Lipids from Ossabaw Pigs Fed the Experimental Diets
| Fatty Acids | Control | Fructose Group | Atherogenic Diet | M-Ath Group | ANOVA P Value |
|---|---|---|---|---|---|
| 12:0 | ND* ± 0.01 | 0.01* ± 0.01 | ND* ± ND | 0.15† ± 0.10 | <0.0001 |
| 14:0 | 0.23*‡ ± 0.07 | 0.38* ± 0.08 | 0.18‡ ± 0.05 | 0.86† ± 0.20 | <0.0001 |
| 15:0 | 0.13† ± 0.02 | 0.06* ± 0.02 | 0.04* ± 0.04 | 0.07* ± 0.04 | 0.0007 |
| 16:0 | 13.98† ± 1.33 | 14.20† ± 0.99 | 10.59* ± 0.99 | 14.38† ± 1.90 | 0.0003 |
| 16:1t | 0.45 ± 0.11 | 0.48 ± 0.07 | 0.53 ± 0.10 | 0.57 ± 0.10 | 0.13 |
| 16:1n7 | 0.41‡ ± 0.13 | 1.00* ± 0.17 | 0.75*‡ ± 0.11 | 2.06† ± 0.38 | <0.0001 |
| 17:0 | 0.55† ± 0.08 | 0.30* ± 0.07 | 0.21* ± 0.04 | 0.29* ± 0.08 | <0.0001 |
| 17:1n7 | 0.14* ± 0.05 | 0.19* ± 0.07 | 0.10* ± 0.02 | 0.33† ± 0.08 | <0.0001 |
| 18:0 | 15.07† ± 1.64 | 16.46† ± 1.39 | 12.75* ± 1.14 | 12.45* ± 0.50 | <0.0001 |
| 18:1t | 0.13 ± 0.12 | 0.06 ± 0.18 | 1.54 ± 2.17 | ND ± ND | 0.04 |
| 18:1n9 | 14.57‡ ± 1.85 | 25.66* ± 2.81 | 27.71* ± 2.79 | 32.74† ± 1.94 | <0.0001 |
| 18:1n7 | 1.66d ± 0.22 | 2.13‡ ± 0.19 | 3.87† ± 0.14 | 3.54* ± 0.10 | <0.0001 |
| 18:1 | 0.04‡ ± 0.04 | 0.07‡ ± 0.10 | 2.83† ± 0.23 | 1.62* ± 0.39 | <0.0001 |
| 18:2n6 | 39.23† ± 2.17 | 29.74* ± 1.67 | 27.89* ± 2.58 | 21.22‡ ± 2.50 | <0.0001 |
| 18:3n6 | 0.28† ± 0.07 | 0.12* ± 0.03 | 0.19†* ± 0.05 | 0.19* ± 0.08 | 0.001 |
| 18:3n3 | 0.87† ± 0.07 | 0.80†* ± 0.09 | 0.49‡ ± 0.05 | 0.69* ± 0.11 | <0.0001 |
| 20:0 | 0.03 ± 0.04 | 0.06 ± 0.05 | 0.03 ± 0.03 | 0.08 ± 0.19 | 0.78 |
| 20:1n9 | 0.16†* ± 0.05 | 0.25† ± 0.03 | 0.08* ± 0.05 | 0.13* ± 0.10 | 0.0002 |
| 20:2n6 | 0.66† ± 0.13 | 0.54†* ± 0.14 | 0.32‡ ± 0.06 | 0.43*‡ ± 0.07 | 0.0005 |
| 20:3n6 | 0.40* ± 0.12 | 0.68† ± 0.14 | 0.93† ± 0.23 | 0.71† ± 0.09 | 0.0002 |
| 20:4n6 | 8.12† ± 2.58 | 4.18* ± 1.01 | 2.94* ± 0.48 | 3.25* ± 0.96 | <0.0001 |
| 20:3n3 | 0.12†* ± 0.05 | 0.16† ± 0.04 | 0.01‡ ± 0.03 | 0.07*‡ ± 0.06 | 0.0002 |
| 20:5n3 | 0.25† ± 0.10 | 0.18†* ± 0.07 | 0.15†* ± 0.02 | 0.10* ± 0.06 | 0.01 |
| 22:0 | 0.01 ± 0.03 | 0.02 ± 0.04 | 0.01 ± 0.03 | ND ± ND | 0.55 |
| 22:1n9 | 0.01 ± 0.03 | ND ± 0.01 | ND ± ND | ND ± ND | 0.45 |
| 22:4n6 | 0.28† ± 0.06 | 0.21†* ± 0.09 | 0.14* ± 0.02 | 0.20†* ± 0.06 | 0.036 |
| 22:5n6 | 0.02 ± 0.03 | 0.01 ± 0.02 | ND ± ND | ND ± ND | 0.12 |
| 22:5n3 | 0.83† ± 0.32 | 0.64†* ± 0.28 | 0.41* ± 0.09 | 0.48†* ± 0.20 | 0.045 |
| 22:6n3 | 0.22 ± 0.05 | 0.47 ± 0.29 | 0.38 ± 0.13 | 0.21 ± 0.17 | 0.08 |
| TOTS | 30.02† ± 2.44 | 31.50† ± 1.95 | 23.80* ± 1.83 | 28.27† ± 2.04 | <0.0001 |
| TOTM | 17.59‡ ± 2.04 | 29.84* ± 2.95 | 37.40† ± 1.91 | 41.00† ± 2.06 | <0.0001 |
| PUFA | 51.29† ± 4.03 | 37.73* ± 2.11 | 33.85* ± 2.39 | 27.55‡ ± 2.74 | <0.0001 |
| n-6 PUFA | 48.99† ± 3.95 | 35.48* ± 1.89 | 32.41* ± 2.42 | 26.00‡ ± 2.66 | <0.0001 |
| n-3 PUFA | 2.30† ± 0.39 | 2.25†* ± 0.63 | 1.44‡ ± 0.18 | 1.55*‡ ± 0.25 | 0.004 |
| n-6 LC | 8.42† ± 2.63 | 4.40* ± 1.06 | 3.08* ± 0.49 | 3.45* ± 1.00 | <0.0001 |
| n-3 LC | 1.31 ± 0.43 | 1.29 ± 0.62 | 0.94 ± 0.19 | 0.79 ± 0.28 | 0.14 |
| TOTS/TOTM | 1.72† ± 0.14 | 1.07* ± 0.18 | 0.64‡ ± 0.06 | 0.69‡ ± 0.06 | <0.0001 |
| TOTM/PUFA | 0.35d ± 0.07 | 0.80‡ ± 0.11 | 1.11* ± 0.12 | 1.51† ± 0.21 | <0.0001 |
| TOTS/PUFA | 0.59‡ ± 0.09 | 0.84* ± 0.07 | 0.71*‡ ± 0.09 | 1.04† ± 0.15 | <0.0001 |
| n-6 LC/n-3 LC | 6.60† ± 1.98 | 3.83* ± 1.41 | 3.35* ± 0.52 | 4.49* ± 0.45 | 0.002 |
| n-6/n-3 | 21.75†* ± 3.32 | 16.70* ± 3.86 | 22.80† ± 3.48 | 17.01* ± 2.30 | 0.007 |
n = 9 for the Fructose group, n = 6 for the M-Ath group, n = 5 for Control and Atherogenic groups.
Values in rows with different symbols are significantly different by one-way ANOVA. The superscripts indicate what mean values are different in the rows, and the P values are for all groups.