Table 4.

Frequency of buried metaplasia following radiofrequency ablation for Barrett's esophagus

Report first author	Degree of neoplasia	Number of patients	Number of biopsies	Mandated surveillance biopsy protocol	Biopsy depth	Duration of follow-up	Percentage of patients found to have buried metaplasia
Herrero et al. (35)	EC, HGD, LGD	24	1,272	Yes	NR	Median 29 months	12.5% (at NSQ junction)
van Vilsteren et al. (36)	HGD, EC	22	NR	Yes	NR	Median 24 months	0%
Fleischer et al. (37)	No dysplasia	50	1,473	Yes	85% LP or deeper	5 Years	0%
Lyday et al. (38)	No dysplasia, IND, LGD, HGD	338 in < 1 year cohort 137 in > 1 year cohort	NR	No	NR	Median 9 months Median 20 months	0% in both cohorts
Pouw et al. (39)	HGD or EC	24	1,201	Yes	NR	Median 22 months	0%
Eldaif et al. (40)	No dysplasia, LGD	27	NR	No	NR	8 Weeks	0%
Pouw et al. (41)	HGD or EC	16	385	Yes	37–51% LP or deeper	Median 26 months	0%
Shaheen et al. (18)	LGD, HGD	84	9,517	Yes	NR	12 Months	5.1%
Sharma et al. (42)	LGD, HGD	62	> 2,500	Yes	NR	Median 24 months	0%
Vassiliou et al. (43)	All grades including no dysplasia	15	NR	Yes	NR	Median 20.3 months	0%
Ganz et al. (44)	HGD	142	NR	No	NR	12 Months	0%
Gondrie et al. (45)	HGD, IMC	12	363	Yes	NR	Median 14 months	0%
Gondrie et al. (46)	HGD, IMC	11	473	Yes	NR	Median 19 months	0%
Hernandez et al. (47)	No dysplasia, LGD, HGD	10	247	Yes	NR	3–38 Months	10%
Pouw et al. (48)	HGD, EC	44	1,475	Yes	NR	Median 21 months	2.7%
Sharma et al. (49)	No dysplasia, LGD	10	886	Yes	NR	2 Years	0%
Roorda et al. (50)	LGD, HGD	13	NR	Yes	NR	Mean 12 months	0%
Sharma et al. (51)	No dysplasia	100	4,306	Yes	NR	12 Months	0%

EC, early cancer; HGD, high-grade dysplasia; IMC, intramucosal cancer; IND, indefinite for dysplasia; LGD, low-grade dysplasia; LP, lamina propria.

Note: A number of reports share the same authors, and we cannot exclude the possibility that some patients were included in more than one series.