Figure 6.

Expression of proinflammatory cytokines. The lipopolysaccharide and K⁹⁰/RGDSK¹⁰ rosette nanotube groups showed significantly higher expression of proinflammatory genes compared with saline controls. Mice treated with K⁹⁰/RGDSK¹⁰ rosette nanotubes following lipopolysaccharide challenge showed significant inhibition of interleukin-1β and MIP-1, and an increase in KC-1 mRNA transcripts when compared with the lipopolysaccharide group. MIP-1 expression did not differ between the lipopolysaccharide and lipopolysaccharide + K⁹⁰/RGDSK¹⁰ rosette nanotube groups.

Note: Groups bearing different superscripts were significantly different (P < 0.05), while the groups with similar superscripts did not differ.