Table 4.
Down regulated genes of MDA-MB-231 cells treated with MAb9E10 antibody 24 and 48 hours (Fold change)
| Symbol | UniGene | Description | 24 h group | 48 h group | |
|---|---|---|---|---|---|
| 1 | CARD9 | Hs.694071 | Caspase recruitment domain family, member 9 | -3.18 | -34.63 |
| 2 | CCL2 | Hs.303649 | Chemokine (C-C motif) ligand 2 | -5.91 | -16.47 |
| 3 | CUL3 | Hs.372286 | Cullin 3 | -20.23 | -10.06 |
| 4 | BIRC3 | Hs.127799 | Baculoviral IAP repeat containing 3 | -3.96 | -9.66 |
| 5 | IL18 | Hs.83077 | Interleukin 18 (interferon-gamma-inducing factor) | -2.05 | -8.89 |
| 6 | TP63 | Hs.137569 | Tumor protein p63 | -3.43 | -8.6 |
| 7 | SPP1 | Hs.313 | Secreted phosphoprotein 1 | -2.88 | -7.61 |
| 8 | TNFRSF21 | Hs.443577 | Tumor necrosis factor receptor superfamily, member 21 | -3 | -6.72 |
| 9 | F2 | Hs.655207 | Coagulation factor II (thrombin) | -35.19 | -5.9 |
| 10 | AIFM3 | Hs.163543 | Apoptosis-inducing factor, mitochondrion-associated, 3 | -1.56 | -5.79 |
| 11 | CARD8 | Hs.446146 | Caspase recruitment domain family, member 8 | -3.07 | -5.52 |
| 12 | PMAIP1 | Hs.96 | Phorbol-12-myristate-13-acetate-induced protein 1 | -4.52 | -4.7 |
| 13 | CD27 | Hs.355307 | CD27 molecule | -2.63 | -4.34 |
| 14 | HMGB1 | Hs.593339 | High mobility group box 1 | -1.74 | -4 |
| 15 | INHA | Hs.407506 | Inhibin, alpha | -5.02 | -3.75 |
| 16 | TP53I3 | Hs.50649 | Tumor protein p53 inducible protein 3 | -1.89 | -3.74 |
| 17 | BRCA1 | Hs.194143 | Breast cancer 1, early onset | -1.99 | -3.49 |
| 18 | MYBL2 | Hs.179718 | V-myb myeloblastosis viral oncogene homolog (avian)-like 2 | -2.42 | -3.32 |