Skip to main content
. 2012 Jan 10;7(1):e29883. doi: 10.1371/journal.pone.0029883

Table 1. Summary of Sex, Age and Minor Allele Frequencies by Cohort.

Cohort
Variable NSHD ELSA HCS HAS Boyd Orr CaPS LBC1921 Total
Number of participants 2618 5515 2902 551 397 867 514 13364
Male, % 50 46 53 59 45 100 41 52
Age* in years, median (range) 53 65 (52–90+) 66 (59–73) 67 (63–73) 70 (64–82) 73 (65–83) 79 (77–80) 65 (52–90+)
Minor Allele Frequencies
rs35767 (IGF1) 0.16 0.15 0.15 0.16 0.16 0.16 0.14 0.15
rs7127900 (IGF2) 0.18 0.18 0.20 0.21 0.19 0.17 0.19 0.19
rs2854744 (IGFBP3) 0.47 0.45 0.46 0.45 0.42 0.46 0.42 0.45
rs2943641 (IRS1) 0.36 0.35 0.35 0.36 0.38 0.35 0.35 0.35
rs2665802 (GH1) 0.41 0.40 0.41 0.41 0.39 0.40 0.41 0.41
d3GHR 0.26 0.27 0.27 0.24 0.27 0.28 0.26 0.27

Numbers of participants represent those with available data for at least one anthropometric or physical capability phenotype and at least one genotype.

*Age at phase from which the majority of variables are taken, i.e. Boyd Orr: III; CaPS: V; ELSA: II; HAS: I; HCS: I; LBC1921: I; NSHD: 1999 Collection. CaPS: Caerphilly Prospective Study; ELSA: English Longitudinal Study of Ageing; HAS: Hertfordshire Ageing Study; HCS: Hertfordshire Cohort Study; NSHD: National Survey of Health and Development.