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. 2012 Jan 10;7(1):e30032. doi: 10.1371/journal.pone.0030032

Figure 7. All A2BR-positive taste cells are Type II cells, indicated by expression of PLCβ2.

Figure 7

Confocal laser scanning microscopy images of double-labeled longitudinal (A′, A″, A) and cross sections (B′, B″, B) of FO taste buds stained for PLCβ2. Although all A2BR-positive cells express the global Type II cell marker, PLCβ2, a subset of PLCβ2-IR cells does not show β-gal (A2BR)-IR (B, C, arrows). Similarly, in CV papillae, all A2BR taste cells (green C′ and C) express PLCβ2 (red in C″ and C) but not vice versa (arrow in panel C). Images of FU taste buds show little β-gal (A2B-R)-IR (green in D′) although PLCβ2 expression (red in D″) is abundant. Rarely, single cells in FU exhibit immunoreactivity for A2BR-driven β-gal as shown in panel E. Scale bars = 20 µm.