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. 2012 Jan 10;9(1):e1001156. doi: 10.1371/journal.pmed.1001156

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This figure shows the “two dimensions” in which PMTCT services can be improved. First, along the vertical arrow, PMTCT programs can transition to more intensive drug regimens (i.e., from sdNVP to Option A to Option B). Second, along the horizontal arrow, programs can undertake interventions to improve “uptake” of PMTCT services, defined as the proportion of pregnant, HIV-infected women who receive and adhere to ARVs for PMTCT, for example, from 36% in 2008 to 56% in 2009, and perhaps to 80% or 95% with future scale-up effort. Within the horizontal arrow are depicted the three “domains” of uptake examined in these analyses: care and testing, drug availability, or retention. sdNVP represents the current National PMTCT Program, based largely on sdNVP; “Option A” and “Option B” are the WHO 2010 PMTCT guideline-recommended regimens, as defined in the text and Text S1.