Table 1c.
Mean (±SD) of each measure by region for each group: FDRI results using phase-guided ROIs and FDRI-guided ROIs
| Region | FDRI (s−1/Tesla), phase-guided ROIs | FDRI (s−1/Tesla), FDRI-guided ROIs | ||||
|---|---|---|---|---|---|---|
| Young (N=11) | Elderly (N=12) | t(elderly>young) | Young (N=11) | Elderly (N=12) | t(elderly>young) | |
| Frontal WM | 2.02 (0.3268) | 1.545 (0.4522) |
t= −2.8643a p=0.0093 |
2.0732 (0.6149) | 1.5976 (0.6144) |
t= −1.8535a p=0.0779 |
| Thalamus | 2.331 (0.5172) | 1.698 (0.6105) |
t= −2.6712a p=0.0143 |
2.2635 (0.5353) | 1.6767 (0.6229) |
t= −2.4115a p=0.0251 |
| Caudate | 2.531 (0.4752) | 3.198 (0.9042) |
t=2.1812 p=0.0407 |
2.5384 (0.3842) | 2.9789 (1.0421) |
t=1.3198 p=0.2011 |
| Putamen | 2.954 (0.4282) | 3.904 (0.738) |
t=3.7284 p=0.0012 |
2.8900 (0.4137) | 3.9732 (0.7612) |
t=4.1820 p=0.0004 |
| Globus Pallidus | 4.223 (0.5178) | 4.497 (0.9267) |
t=0.8642 p=0.3972 |
4.8961 (0.4369) | 5.5338 (1.0121) |
t=1.9285 p=0.0674 |
| Substantia Nigra | 3.225 (0.9541) | 3.421 (0.9988) |
t=0.4804 p=0.6359 |
3.1479 (0.9576) | 3.9619 (0.9641) |
t=2.0290 p=0.0553 |
| Red Nucleus | 3.268 (0.9763) | 3.932 (0.8528) |
t=1.7415 p=0.0962 |
3.1284 (0.8765) | 3.99916 (0.7634) |
t=2.5240 p=0.0197 |
| Dentate Nucleus | 2.41 (0.7971) | 2.533 (0.8682) |
t=0.3546 p=0.7264 |
2.0137 (0.5972) | 1.9244 (0.5801) |
t=−0.3637 p=0.7196 |
p-values are 2-tailed. Numbers in bold indicate significant differences, family-wise Bonferroni corrected based on one-tailed directional hypotheses, requiring p ≤.0.0125 for 8 comparisons.
a
Negative t values indicate a group difference with the elderly having less iron than the young.