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. Author manuscript; available in PMC: 2013 Jan 1.
Published in final edited form as: Toxicol Appl Pharmacol. 2011 Oct 18;258(1):51–60. doi: 10.1016/j.taap.2011.10.007

Fig. 4.

Fig. 4

Western blot analysis show changes in caspase 9, 8, and 3. (A) Digitoxin and D6-MA induced differential cleavage of caspase 9. Digitoxin caused pro-caspase 3 to drop at 50 nM, while D6-MA caused pro-caspase 3 to drop at 20 nM. (B) Quantification of cleaved caspase 9 blots shows fold change in cleavage following treatment. (C) Quantification of cleaved caspase 8 blots shows fold change in cleavage following treatment. (D) Quantification of pro-caspase 3 blots shows decrease in quantity following treatment; (*) indicates significantly different from control, (†) indicates significantly different from digitoxin.