Table 5.
Sociodemographic and clinical correlates§ of Glucosamine/Chondroitin Use, Other CAM use use among participants with radiographic confirmed knee osteoarthritis
| Glucosamine/Chondroitin Use Only (N=373) | Other CAM Use Only (N=245) | |
|---|---|---|
| Adjusted odds ratios (95% Confidence Intervals) | ||
| Age ≥ 65 years | 1.26 (0.95–1.67) | 1.10 (0.79–1.53) |
| Women | 1.66 (1.26–2.18) | 2.25 (1.61–3.14) |
| Race/ethnicity | ||
| Black | 0.39 (0.24–0.65) | 1.09 (0.72–1.63) |
| Latino | 0.47 (0.10–2.21) | 0.82 (0.18–3.86) |
| Other | 1.74 (0.80–3.78) | 2.52 (1.12–5.67) |
| Non–Hispanic White | 1.0 | 1.0 |
| Education | ||
| ≥College graduate | 2.18 (1.42–3.34) | 1.19 (0.78–1.82) |
| Some college | 1.37 (0.85–2.22) | 1.21 (0.77–1.90) |
| High school or less | 1.0 | 1.0 |
| Body Mass Index | ||
| Morbid obesity | 0.56 (0.32–0.96) | 0.73 (0.40–1.35) |
| Obesity | 0.81 (0.55–1.17) | 1.19 (0.75–1.89) |
| Overweight | 0.78 (0.56–1.10) | 1.12 (0.72–1.75) |
| Normal weight | 1.0 | 1.0 |
| Depression | 0.50 (0.26–0.94) | 1.16 (0.68–1.95) |
| SF-12 Physical Scale # | 0.98 (0.81–1.19) | 0.78 (0.64–0.96) |
| WOMAC – Pain # | 0.92 (0.73–1.15) | 1.14 (0.90–1.45) |
| KOOS – QOL # | 0.63 (0.51–0.76) | 0.80 (0.63–1.01) |
| History of knee injury/surgery | 1.35 (1.02–1.78) | 1.16 (0.85–1.59) |
| Hip replacement | 1.72 (0.55–5.36) | 1.00 (0.21–4.75) |
| Multi-joint osteoarthritis: | 1.35 (1.03–1.77) | 1.41 (1.02–1.95) |
| Chair stands (seconds) | 0.96 (0.91–1.00) | 0.99 (0.94–1.04) |
| OARSI* grade | ||
| Grade 3 (severe) | 2.20 (1.48–3.26) | 1.02 (0.63–1.64) |
| Grade 1–2 (narrowed) | 1.33 (0.98–1.81) | 0.90 (0.65–1.26) |
| Grade 0 (normal) | 1.0 | 1.0 |
Reference group for the outcome includes patients who did not report use of CAM or conventional medications for osteoarthritis treatment. Odds ratios shown are adjusted for all variables shown on the table. Results for Conventional Medications Only and Users of Both CAM and Conventional Medications are not shown as the odds ratios are virtually the same as those shown in Table 4.
Odds ratios are per one standard deviation change in SF-12 Physical Scale (standard deviation=9.5), WOMAC Pain Scale (standard deviation=4.0), and KOOS QOL scale (standard deviation=23.1).
X-ray evidence of joint space narrowing.