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Effect of other KCNQ blockers on ICC outward current. A, ICCs were stepped from −60 to 40 mV. Control current was decreased by 10 and 30 μM linopirdine. ms, milliseconds. B, outward currents were also sensitive to 10 and 30 μM chromanol 293B. C, effect of linopirdine in 5 cells. Asterisk indicates p <0.05. C and D, effect of chromanol in 11 cells.
