Table 2.
Differentially nitrotyrosinylated proteins identified by MALDI-TOF PMF. Each protein in the list demonstrated increases in the mean value of tyrosine nitration when compared to the young (4-month-old) control group, but only those significant by ANOVA analysis are indicated by arrows in the far right 3 columns.
| Swiss Prot ID | SSP# | Annotation | pI | Mass | 4→12 | 4→24 | 4→34 |
|---|---|---|---|---|---|---|---|
| Q9ER34 | 6506 | Aconitase 2, mitochondrial | 8.2 | 88.39 | - | - | - |
| Q5TF02 | 4602 | Adenosine monophosphate deaminase 1 | 6.5 | 89.24 | - | - | - |
| Q64057 | 6318 | Aldehyde dehydrogenase family 6 | 8.9 | 59.59 | - | - | - |
| Q5M7U6 | 4312 | ARP2 actin-related protein 2 homolog | 6.3 | 46.05 | - | ↑ | ↑ |
| O88501 | 4501 | Calpain 6 | 6.9 | 77.18 | - | - | - |
| P07632 | 3006 | Dismutase | 5.9 | 16.11 | - | ↑ | ↑ |
| Q6I7R1 | 4503 | Down-regulated in nephrectomized rat kidney | 6.2 | 68.99 | - | - | - |
| P04764 | 3306 | Enolase 1 protein | 6.7 | 53.26 | - | - | - |
| P04797 | 6202 | Glyceraldehyde-3-phosphate dehydrogenase | 8.7 | 37.24 | - | - | - |
| P83581 | 2503 | Heat Shock Protein 70 | 5.5 | 72.29 | ↑ | ↑ | - |
| Q9ESM0 | 6314 | Inositol hexaphosphate kinase 1 | 6.8 | 51.03 | - | ↑ | ↑ |
| Q80YG1 | 6208 | Phosphoserine aminotransferase | 8.5 | 41.92 | - | - | - |
| Q04631 | 2303 | Protein geranylgeranyltransferase type I, beta subunit | 6.2 | 43.97 | - | ↑ | - |
| Q63477 | 6508 | Protein tyrosine phosphatase epsilon C | 7.2 | 78.91 | - | - | - |
| P52847 | 6209 | Sulfotransferase family cytosolic 1B member 1 | 8.4 | 36.39 | - | ↑ | ↑ |
| P80204 | 3411 | TGF-beta receptor type-1 precursor | 7.3 | 58.22 | - | ↑ | - |
| P81155 | 6210 | Voltage-dependent anion channel 2 | 7.7 | 33.32 | - | - | - |