Table 2.
Laboratory and diagnostic testing considerations for the acute pediatric stroke patient.
| Additional laboratory tests to consider | Additional tests to consider |
|---|---|
| Liver function | Brain MRI |
| ESR | MRA |
| CRP | (i) Intracranial vessels |
| Pregnancy | (ii) Extracranial great vessels (neck) |
| ANA | MRV |
| Lupus anticoagulant | Diffusion weighted imaging (DWI) |
| Anticardiolipin antibody | CT angiogram |
| Beta-2 glycoprotein-1 antibody | (i) Intracranial vessels |
| Activated protein C resistance | (ii) Extracranial great vessels (neck) |
| Factor V Leiden mutation | Contrast transthoracic echo (TTE) |
| Protein S/C function | Cerebral angiogram |
| Antithrombin III | Contrast transesophageal echo (TEE) |
| Prothrombin gene mutation | Electroencephalogram (EEG) |
| Homocysteine level | Lumbar puncture |
| Methyltetrahydrofolate reductase allele (MTHFR) | Holter monitoring |
| Fibrinogen disorder | Transcranial doppler |
| Plasminogen activator inhibitor disorder | |
| Factor VII/VIII elevation | |
| Factor XII deficiency | |
| Plasma amino acids/urine amino and organic acids | |
| Serum and CSF lactate/pyruvate | |
| Hemoglobin electrophoresis | |
| Triglycerides/cholesterol | |
| Lipoprotein (a) | |
| Miscellaneous bacterial, fungal, spirochetal, parasitic, | |
| viral, and rickettsial tests (i.e., Lyme, PPD, VDRL) | |
| Serum and CSF varicella titers | |
| HIV titers |