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. 2011 Aug 26;1(8):e32. doi: 10.1038/bcj.2011.32

Figure 5.

Figure 5

Expression profiles of the four kinase genes in imatinib-resistant patients and good responders. Twelve CML samples were collected, six poor responders (P) containing three chronic phase (CP) and three acute phase (AP); six good responders (G) containing three CPs and three APs. qRT-PCR was performed for the 12 samples as described in Materials and methods section using the same primers listed in Table 1. All three chronic phase poor responders showed relative upregulation of AURKC expression compared with good responders. However, the other three kinase genes did not show prominent difference of expression between the poor and good responders.