Figure 4.

Differentially expressed miRNAs in WM. All samples derived from patients with WM (CD19⁺, CD138⁺, CD19⁺CD138⁺) were combined into one group (n=17) for analysis and compared with miRNA expression in (a) CD19⁺ CLL, (b) CD138⁺ MM and (c) NM (CD19⁺, CD138⁺, CD19⁺CD138) cells. Values are fold-change in expression relative to CLL, MM or NM cells, respectively. Specific miRNA were considered to be significantly differentially expressed based on a cutoff P-value <0.001 and an absolute fold-change in expression of greater than two. Only known human miRNAs derived from the Sanger miRBase were considered for analysis.