Fig. 7.

(A) Fluorescence, (B) OCT, and (C) histology of adenoma (AD) in mouse upper colon. The adenoma almost triples the thickness of the mucosal layer in the inflamed area (mucosal thickening-MT). The adjacent normal mucosa (M), submucosa (SM), and muscularis propria (MP) are labeled. Accumulation of PCL microparticles (PCLMPs) in the adenoma area is visible in the OCT image and confirmed by histology. Individual PCLMPs are discernable in the magnified (x40) histology area. OCT scale bar: 250 μm; Histology magnification: 5x and 40x, respectively