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. 2011 Dec;6(12):2838–2845. doi: 10.2215/CJN.00300111

Table 1.

Descriptive statistics for representative transplant recipients and donor comorbidities and outcomes over time

1996 to 2009 1998 2002 2006 P for Trend
Total number of recipients 150,075 12,485 14,573 15,813
Recipient age and demographics
    age between 21 and 30 years 10.99% 12.91% 10.04% 8.84% <0.001
    age between 31 and 50 years 45.44% 50.72% 45.85% 38.04% <0.001
    age between 51 and 60 years 25.62% 23.13% 26.18% 28.76% <0.001
    age greater than 60 years 17.85% 13.24% 17.93% 24.35% <0.001
    male 59.76% 59.14% 59.23% 61.44% 0.01
Comorbidities
    recipient has diabetes 26.35% 25.91% 27.42% 27.62% 0.01
    recipient was on dialysis 75.34% 77.41% 77.19% 75.89% 0.27
    recipient had heart or vascular disease 18.87% 18.47% 18.29% 20.49% <0.001
    recipient had hypertension 74.84% 69.75% 76.63% 81.18% <0.001
    recipient had prior transplant(s) 11.71% 11.43% 11.54% 12.08% 0.22
Wait
    average wait time in years (for deceased donor recipients) 1.98 1.63 2.08 2.12 <0.001
Recipient outcomes
    3-year graft survival 82.16% 81.66% 82.42% 84.82% <0.001
    3-year patient survival 90.28% 90.29% 90.29% 91.73% 0.32
Outcome variation across center
    standard deviation of unadjusted 3-year graft survival 16.1% 7.84% 8.60% 7.30% 0.72
    standard deviation of unadjusted 3-year patient survival 17.0% 5.14% 6.35% 5.59% 0.76
Donor characteristics
    deceased donor 63.8% 68.7% 61.6% 62.6% <0.001
    expanded criteria donors 10.85% 10.46% 8.50% 12.35% <0.001
    average total HLA antigen mismatches (A, B, and DR loci) 3.39 3.13 3.33 3.60 <0.001
    average HLA-A antigen mismatches 1.19 1.14 1.18 1.23 <0.001
    average HLA-B antigen mismatches 1.29 1.16 1.25 1.40 <0.001
    average HLA-DR antigen mismatches 1.14 1.08 1.13 1.19 <0.001
    peak panel reactive antibody (PRA) 12.02 11.57 11.83 12.10 <0.001
    donor weight (kg) 75.89 72.89 74.87 78.34 <0.001
    donor age 38.34 36.65 37.61 39.54 <0.001
    cold ischemia time (hours) 13.93 15.20 13.37 13.23 <0.001
    donor history of diabetes 3.10% 2.19% 3.38% 4.34% <0.001
    donor history of hypertension 18.42% 19.23% 18.74% 18.19% 0.23