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. 2011 Dec 5;30(1):71–77. doi: 10.1200/JCO.2011.38.4594

Table 2.

Prevalence of Pretransplantation Comorbidities and Cumulative Incidence of New Post-HCT Late Effects at 5 Years After HCT, With Median and IQR of Time to Diagnosis

Pretransplantation Comorbidities and/or New Post-HCT Late Effects Autologous
Allogeneic
P for Autologous vAllogeneic Transplantation
Pretransplantation Prevalence (%) Cumulative Incidence Since Transplantation
Days to Diagnosis
Pretransplantation Prevalence (%) Cumulative Incidence Since Transplantation
Days To Diagnosis Median (IQR)
% SE Median IQR % SE Median IQR
Avascular necrosis 0.2 4.3 1.3 411 86-811 0.5 4.6 0.9 514 340-635 .32
Joint replacement 1.8 4.2 1.3 1,098 463-1,199 1.4 3.0 0.8 645 362-766 .92
Osteoporosis 2.4 9.7 1.7 420 229-500 1.4 23.0 1.9 364 223-464 < .001
Thyroid disease 7.5 14.2 1.8 353 204-679 9.8 13.3 1.6 385 286-612 .66
Diabetes mellitus 6.1 3.0 1.0 580 212-1,104 8.3 22.9 1.8 216 153-353 < .001
Adrenal insufficiency 0.2 1.3 0.8 1,236 140-1,437 0.2 13.4 1.5 340 166-413 < .001
Cerebrovascular disease 0.6 1.1 0.5 137 137-177 1.2 1.8 0.6 476 143-716 .51
Coronary artery disease 3.5 1.9 1.0 1,444 778-1,447 3.0 2.7 0.8 453 329-1,059 .14
Iron overload 0.2 0.7 0.4 392 334-572 2.2 25.4 2.0 363 227-432 < .001
Obstructive/restrictive lung disease 1.6 8.2 1.3 369 330-392 1.5 36.9 2.1 363 235-504 < .001
Organ transplantation 0 0.3 0.3 803 0.2 .19
Suicide or suicide attempt 0.2 0.3 0.3 737 0.7 0.9 0.5 671 393-1,045 .27
Deep venous thrombosis(not catheter associated) 7.5 5.6 1.1 137 67-371 3.7 10.9 1.4 343 210-572 .01
Dialysis 1.4 2.3 0.8 204 77-776 0 2.0 0.6 460 362-662 .94

Abbreviations: HCT, hematopoietic cell transplantation; IQR, interquartile range.