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. Author manuscript; available in PMC: 2012 Jan 11.
Published in final edited form as: Tuberculosis (Edinb). 2009 Sep 15;89(5):334–353. doi: 10.1016/j.tube.2009.05.008

Table 12.

Antitubercular activities of representative thienopyrimidinamines

graphic file with name nihms-146470-t0021.jpg
Cpd. No. R1 R2 TB IC90 SI
22a 6-methyl-2-pyridyl H 4.6 >3.3
22b Me 1,1-dimethylpropyl 24 >0.6
22c 2-phenylethyl H 28 >0.5