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. Author manuscript; available in PMC: 2012 Jan 11.
Published in final edited form as: Tuberculosis (Edinb). 2009 Sep 15;89(5):334–353. doi: 10.1016/j.tube.2009.05.008

Table 15.

Antitubercular activities of representative thienoisoxazole 4,4-dioxides

graphic file with name nihms-146470-t0024.jpg
Cpd.No. R1 TB IC90 SI
26a 4-chloro 1.4 >10
26b 4-trifluoromethyl 3.4 3.6
26c 2,6-dichloro 12 >1.2