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Virus infection of intracranial U87 tumors. Athymic mice with established intracranial U87 gliomas were treated with G47δ-empty or G47δ-mAngio (N = 3) injected directly into the tumor and sacrificed 6 hours later. Frozen brains were cut through the whole tumor area and analyzed for viral distribution. Lac Z staining (staining of viral β-galactosidase activity, blue) of two representative tumors treated with G47δ-mAngio or G47δ-empty at the anterior, central and posterior tumor area.
