Skip to main content
. 2011 Sep 13;20(1):37–45. doi: 10.1038/mt.2011.187

Figure 6.

Figure 6

Kaplan–Meier analysis of survival with combination treatment. (a) Survival of mice treated with intratumoral (IT) phosphate-buffered saline (PBS) and i.v. PBS (PBS); IT PBS + i.v. BEV (bevacizumab (BEV), 5 mg/kg); IT PBS + i.v. BEV (BEV, 10 mg/kg); IT PBS + i.v. BEV (BEV, 30 mg/kg); IT G47δ-empty + i.v. BEV (BEV+empty); IT G47δ-mAngio + i.v. BEV (BEV+mAngio); and IT G47δ-mAngio + i.v. PBS [mAngio, 1 × 106 plaque-forming unit (pfu)/mice]. The P values for each pair wise comparison are indicated. (b) Masson's trichrome staining for collagen deposits (blue) and immunohistochemistry staining for matrix metalloproteinase-2 (MMP2) and MMP9 expression (dark brown) in mice brain carrying the U87 glioma treated with 5 mg BEV/kg and IT G47δ-mAngio + i.v. BEV (BEV+mAngio). The bar indicates 0.5 mm.