Table 5.
Proteins differentially expressed by change in growth rates
Protein and category | Name or function | Log2 growth rate (h−1) ratio |
|
---|---|---|---|
0.05/0.15 | 0.4/0.15 | ||
Amino acid biosynthesis | |||
EF2550 | Serine hydroxymethyltransferase | −1.04 | −0.79 |
Biosynthesis of cofactors, prosthetic group, carriers | |||
EF1860 | 3-Methyl-2-oxobutanoate hydroxymethyltransferase | 0.52 | 0.75 |
EF0901 | Isopentenyl diphosphate delta isomerase, putative | 0.63 | 1.1 |
Cell envelope | |||
EF2193 | dTDP-4-dehydrorhamnose 3,5-epimerase | −0.30 | 0.79 |
EF2194 | Glucose-1-phosphate thymidyltransferase | −0.26 | 0.59 |
EF3183 | Cell wall surface anchor family protein | 1.00 | 0.44 |
Cellular processes | |||
EF0080 | Gls24 protein | −0.15 | −0.5 |
EF1744 | General stress protein | 1.30 | 1.46 |
EF1991 | Cold shock protein CspC | −0.25 | 0.42 |
EF3312 | tRNA modification GTPase TrmE | 1.01 | 1.63 |
DNA metabolism | |||
EF0002 | DNA polymerase III, beta subunit | 0.65 | 0.32 |
EF0883 | Primosomal DnaI | −0.60 | 1.15 |
Energy metabolism | |||
EF0020 | Phosphotransferase system, mannose-specific IIAB components | −0.15 | −1.3 |
EF0195 | Phosphoglycerate mutase 1 | −0.33 | 0.52 |
EF0949 | Phosphotransacetylase | 0.30 | 0.54 |
EF1125 | Putative l-ascorbate 6-phosphate lactonase | 0.02 | 0.61 |
EF1131 | l-Ribulose-5-phosphate 4-epimerase | 0.39 | 0.75 |
EF1167 | Fructose-bisphosphate aldolase | 0.77 | 0.24 |
EF1353 | Pyruvate dehydrogenase complex E1 component, alpha subunit | 0.30 | 0.94 |
EF1354 | Pyruvate dehydrogenase complex E1 component, beta subunit | −0.12 | 0.65 |
EF1356 | Dihydrolipoamide dehydrogenase | −0.53 | −1.64 |
EF1416 | Glucose-6-phosphatase isomerase | −0.02 | −0.89 |
EF1526 | Glyceraldehyde-3-phosphate dehydrogenase | 0.08 | −0.95 |
EF1612 | Pyruvate formate-lyase activating enzyme | 0.24 | −1.18 |
EF1962 | Triosephosphate isomerase | 0.04 | 0.73 |
EF1963 | Phosphoglycetare kinase | −0.37 | −0.2 |
EF1964 | Glyceraldehyde-3-phosphate dehydrogenase | 0.35 | −1.07 |
EF0283 | 3-Oxoacyl-(acyl carrier protein) synthetase II | −0.12 | −0.91 |
Fatty acid and phospholipid metabolism | |||
EF2875 | Acetyl-CoA carboxylase subunit alpha | 0.00 | 0.89 |
EF2881 | 3-Ketoacyl-(acyl carrier protein) reductase | −0.36 | 1.10 |
EF2882 | Acyl carrier protein S-malonyltransferase | 0.00 | 0.54 |
Hypothetical proteins | |||
EF1227 | Hypothetical protein | −0.99 | 0.26 |
EF1241 | Hypothetical protein | −0.14 | 0.11 |
EF1560 | Hypothetical protein | 0.47 | 0.91 |
Protein fate | |||
EF2200 | Methionine aminopeptidase | −0.48 | 0.70 |
F2898 | Peptidyl-prolyl cis trans isomerase | 0.75 | 0.74 |
EF3066 | Peptide deformylase | 0.81 | 1.48 |
Protein synthesis | |||
EF0212 | 30S ribosomal protein S3 | 0.97 | 1.39 |
EF0221 | 50S ribosomal protein L6 | 0.60 | 0.72 |
EF0701 | Peptide chain release factor 3 | 0.36 | 1.22 |
Purines, pyrimidines, nucleosides, and nucleotides | |||
EF0228 | Adenylate kinase | 0.61 | 1.59 |
EF1713 | Orotidine 5′-phosphate decarboxylase | 0.57 | 0.91 |
EF1721 | Bifunctional pyrimidine regulatory protein PyrR uracil phosphoribosyltransferase | −1.16 | 0.61 |
EF2549 | Uracil phosphoribosyltransferase | 0.04 | 0.60 |
EF3293 | Inositol-5-monophosphate dehydrogenase | 0.08 | −0.79 |
Regulatory functions, signal transduction, transcription, and transport and binding proteinsa | |||
EF1741 | Catabolite control protein A | 0.25 | 0.38 |
EF3289 | DNA-binding response regulator | 0.82 | 1.31 |
EF1050 | DNA-binding response regulator | 0.38 | 1.04 |
EF0233 | DNA direct RNA polymerase subunit alpha | 0.50 | −0.26 |
EF0865 | Glycine betaine/carnitine/choline transporter, ATP-binding protein | −0.24 | −0.54 |
Unknown function | |||
EF0076 | Oxidoreductase short chain dehydrogenase/reductase family | 0.31 | −1.64 |
EF0877 | Aldo-/keto-reductase family oxidoreductase | −0.64 | 0.48 |
EF1138 | Aldo-/keto-reductase family oxidoreductase | −0.45 | 0.23 |
EF2591 | Glyoxalase family protein | 0.54 | 1.07 |
EF2656 | Flavoprotein family protein | 0.97 | 1.16 |
EF2927 | Haloacid dehydrogenase superfamily hydrolase | 0.92 | 2.04 |
EF1741 and EF3289 have regulatory functions; EF1050 is involved in signal transduction; EF0233 is involved in signal transcription; and EF0865 is involved in transport and binding.