Fig 2.

Summary of engineered pathway to convert fatty acids to methyl ketones in E. coli DH1. Green boxes indicate overexpressed genes, and red boxes indicate chromosomal deletions. The blue box indicates the putative substrate for FadM (producing free β-keto acids), and the purple box indicates the final methyl ketone product (putatively generated by spontaneous decarboxylation of β-keto acids). The ′TesA thioesterase used for fatty acid overproduction is not depicted in this figure.