Table 3.
Disease outcomes in negative (sham-inoculated)- and positive (Sakai-inoculated)-control group and experimental (CG or BBG)-group piglets
| Disease outcome | Value (mean ± SEM) for piglet groupa |
|||
|---|---|---|---|---|
| Negative control (n = 4) | Positive control (n = 4) | CG (n = 10) | BBG (n = 10) | |
| Clinical scorec | 0.98 ± 0.34A | 3.96 ± 0.26AB | 4.12 ± 0.66B | 1.5 ± 0.45A |
| CNS disease scorec | 0.07 ± 0.07A | 2.35 ± 0.28B | 2.39 ± 0.46B | 0.69 ± 0.25A |
| Survival time (days) | 7.00 ± 0.00A | 4.25 ± 0.63AB | 3.70 ± 0.06B | 6.20 ± 0.55A |
| Intestinal bacterial load (log10 CFU)b | 1.13 ± 0.47C | 5.85 ± 0.17B | 5.09 ± 0.19B | 4.30 ± 0.18A |
| Histopathological score for intestine | 1.00 ± 0.39 | 2.88 ± 0.79 | 2.01 ± 0.49 | 1.08 ± 0.37 |
a
Groups not sharing specific letters differed significantly (P ≤ 0.05).
b
Average intestinal bacterial load (log10 CFU) from five segments of the intestine (ileum, cecum, spiral colon, distal colon, and RAJ).
c
Clinical score is the daily mean of the total clinical score based on all five categories in Table 2, whereas CNS disease score is the daily mean score of the CNS category only.