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. 2012 Jan;32(1):226–239. doi: 10.1128/MCB.06166-11

Fig 10.

Fig 10

TFEB-independent mechanism of GATA-1-mediated lysosomal gene activation. (A) TFEB knockdown strategy in G1E-ER-GATA-1 cells. (B) siRNA-mediated knockdown of Tcfeb expression in untreated and β-estradiol-treated G1E-ER-GATA-1 cells. Quantitative RT-PCR analysis of Tcfeb (B), autophagy (C), and lysosomal (D) gene transcripts in TFEB knockdown G1E-ER-GATA-1 cells (mean ± standard error; 4 to 5 independent experiments; ∗, P < 0.05; ∗∗, P < 0.01). Values were normalized to 18S rRNA expression levels.