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. 2012 Jan;32(1):126–138. doi: 10.1128/MCB.06077-11

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Fig 5 — SMN deficiency impairs exon 7 splicing in SMA motor neurons. Analysis of the relative efficiency of exon 7 inclusion in the whole spinal cord (A) as well as motor neurons (LCM MNs) and non-motor neurons (LCM non-MNs) (B) isolated from control (Smn^+/−; SMN2^+/+; SMNΔ7^+/+; GFP^+/−) and Δ7 SMA (Smn^−/−; SMN2^+/+; SMNΔ7^+/+; GFP^+/−) mice at postnatal day 6. Normalized exon 7 inclusion was measured by real-time RT-qPCR analysis of the expression of full-length (SMN2_FL) relative to total (SMN2_TOT) SMN2 mRNAs. Values represent means and SEM from independent experiments (n=8; *, P < 0.05).