Table 2.
Genotype | Male fertility | Avg litter size (males) | Mean testis/body wt (×10−3) ± SD | Female fertility | Avg litter size (females) |
---|---|---|---|---|---|
+/+ | 28/28 | 6.2 | ND | 28/28 | 6.2 |
+/– | 29/29 | 6.7 | 3.1 ± 0.37 (n = 3) | 19/19 | 5.8 |
–/– | 11/0 | 0 | 2.92 ± 0.31 (n = 6) | 10/10 | 5.2 |
To test fertility, sexually mature mice were bred for at least 3 months. Litter size was recorded for each mating. Testis weight and body weight were measured from mice older than 5 months of age. ND, not determined.