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. 2012 Jan;32(2):490–500. doi: 10.1128/MCB.06361-11

Fig 2.

Fig 2

Lack of Akt1 upregulates bone-specific alkaline phosphatase activity during osteogenic differentiation. Quantitative assessment of AP activity during BMP2-induced osteoblast differentiation for up to 15 days. (A) C3H10T1/2 cells. (B) Mouse bone marrow stromal cells (MSC). (C) Embryo fibroblasts (MEFs) from wild-type (WT) or Akt1 knockout (KO) mice (mean ± SD of results of three experiments; ∗, P < 0.05; ∗∗, P < 0.01 versus Con or WT).