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Effect of the miR-122 3′-tail interaction on HCV replication. Values were normalized to the signal obtained for WT HCV in the absence of additional microRNA (addition of miR-124 had no effect). Error bars denote 1 standard deviation, as determined from 5 separate experiments, with each experiment consisting of four replicates, which were averaged together. Red lines denote statistically significant differences (P < 0.001) between the indicated conditions.
