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EIA cross-reactivity of anti-GII.4-2002 MAbs to NoV VLPs. Purified MAbs were assayed by EIA for reactivity to GI and GII NoV VLPs. (A) MAbs with cross-genogroup reactivity. (B) MAbs with cross-genotype reactivity. Bars represent means with standard errors. Positive reactivity was defined as a mean optical density (OD) at 405 nm ≥3 time that of the background (dashed line). Asterisks indicate VLPs with reactivity significantly different from that of GII.4-2002.
