Table 1.
Group | No. of animals | Vaccinationa | SIV-specific CTL response postboost |
---|---|---|---|
I | 6 | None | None |
II | 5 | Gag (pCMV-SHIVdEN DNA prime, SeV-Gag boost) | Gag-specific CTL |
III | 6 | Gag241-249-specific (pGag236-250-EGFP-N1 DNA prime, SeV-Gag236-250-EGFP boost) | Gag241-249-specific CTL |
IV | 5 | Gag206-216-specific (pGag202-216-EGFP-N1 DNA prime, SeV-Gag202-216-EGFP boost) | Gag206-216-specific CTL |
All animals were challenged with SIVmac239.