Fig 6.

Antigenic analysis of viral variants using the hemagglutination inhibition (HI) assay and MAbs prepared against capsids of FPV (red), CPV-2 (blue), or CPV-2b (black). The results are expressed as comparisons of HI titers to those with the original capsid. Four different viruses from raccoons were tested, along with the FPV, CPV-2, and CPV-2b prototypes (FPV/Cat/NY/292/68, CPV-2/Dog/NY/CPV-d/79, CPV-2b/Dog/TX/CPV-39/84) and the 300Asp mutant of CPV-2 (CPV-2/Dog/NY/CPV-d/79:300D). Filled rectangles indicate binding within ±2-fold of the original titer; shaded rectangles, 4- to 16-fold reductions in titer; open rectangles, >16-fold reductions in titer.