Fig 9.

Effect of RS-1 on PFV replication in HeLa cells. (A) Effect of RS-1 treatment on hRAD51 DNA repair endogenous activity. The ability of RS-1 to promote cisplatin resistance was checked in a standard survival analysis after 24 h of treatment with increasing concentrations of the compound. (B) Effect of RS-1 treatment on PFV replication in HeLa cells. HeLa cells pretreated or not with increasing concentrations of RS-1 were infected with PFV at a MOI of 0.4. Replication was quantified by fluorescence-activated cell sorting (FACS) 48 h postinfection. All results are the means from at least three representative independent experiments ± standard deviations (error bars). A Student test was performed on serial values. *, P < 0.05.