Table 2.

Intrapatient d_N/d_S ratios of type 1 and type 2 HERV-K (HML-2) RNA sequences over three time points in plasma from HIV-1-positive patients

Patient	Type 1					Type 2
	No. of sequences	dN	dS	dN/dS ratio	P valuea	No. of sequences	dN	dS	dN/dS ratio	P valuea
1	27	0.0325	0.0730	0.44	<0.001	3	0.0068	0.0424	0.16	<0.001
2	30	0.0378	0.0606	0.62	<0.001	6	0.0975	0.1494	0.65	<0.001
3	40	0.0318	0.0618	0.51	<0.001	22	0.0920	0.1977	0.46	<0.001
4	27	0.0461	0.1180	0.39	<0.001	34	0.1104	0.1684	0.65	<0.001
5	28	0.0371	0.0651	0.56	<0.001	33	0.0768	0.1511	0.50	<0.001
6	31	0.0548	0.0964	0.56	<0.001	17	0.0819	0.1960	0.41	<0.001

^aStatistical significance taken from the log likelihood Z test. P values reflect comparisons of the d_N/d_S ratios obtained in this study to the null hypothesis (d_N/d_S = 1).