Table 4.
TAP-independent ligands and epitopes and their hydrophobicity
| Ligand(s) or epitope(s) | Protein | Virus | Hydrophobicitya | Reference(s) or source |
|---|---|---|---|---|
| LLWTLVVLL | LMP2 | EBV | 2.9 | 38 |
| CLGGLLTMV | LMP2 | EBV | 2.1 | 38 |
| 8 TAP− epitopes (mean ± SD) | EBV | 2.5 ± 0.2 | 38 | |
| MLDDFSAGA | A17L9-17 | Vaccinia virus | 0.4 | This study |
| SPEGEETII | A10L614-623 | Vaccinia virus | −0.6 | This study |
| ILDRIITNA | A10L688-696 | Vaccinia virus | 0.8 | This study |
| SRGYFEHMKK | A10L867-876 | Vaccinia virus | −1.7 | This study |
| WQTMYTN | B8R53-59 | Vaccinia virus | −1.2 | This study |
| YRLQGFTNAGIVAYK | K2L16-30 | Vaccinia virus | −0.1 | This study |
| IAMKRTLLEL | D5R148-157 | Vaccinia virus | 0.7 | This study |
| LPFGSLGI | A50R294-301 | Vaccinia virus | 1.5 | This study |
| IPSPGIMLV | C11R101-110 | Vaccinia virus | 1.6 | This study |
| MLDDFSAGAGVLDKDL | A17L9-25 | Vaccinia virus | 0.3 | This study |
| DGLIIISI | D8L112-119 | Vaccinia virus | 2.1 | This study |
| 11 TAP− ligands (mean ± SD) (P < 0.0001) | Vaccinia virus | 0.3 ± 1.2 | This study | |
| 79 TAP+ epitopes (mean ± SD) | Vaccinia virus | 0.4 ± 1.0 | 26, 46 |
a
Values correspond to the grand average of hydropathicity (GRAVY) scale (ProtParam tool [ExPASy Proteomics Server; http://www.expasy.ch).