Fig 6.

Role of Mbs1 in genotoxic and oxidative stress response. Each C. neoformans strain described in Fig. 3B was grown overnight at 30°C in liquid YPD medium, 10-fold serially diluted (1 to 10⁴ dilutions), and spotted (3 μl of dilution) on YPD agar containing the indicated concentrations of HU (70 mM) or TBZ (11 μg/ml) for genotoxic stress susceptibility test (A) and H₂O₂ (2.5 mM) or diamide (3 mM) for oxidative stress susceptibility test (B).