Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Alignment of the amino acid residues of the coding regions of DBPII-SalI and DEKnull. The gene coding for the ligand domain of DBPII-SalI was used as a template to create a novel synthetic DBPII allele (DEKnull). The most highly variant cluster of polar charged residues within the dominant B-cell epitope (underlined) identified in a previous study (12) was mutated to either alanine, threonine, or serine. Asterisks show different polymorphic sites within the DBP region II (39).
